We examined a natural history of opioid overdose deaths from 1999-2021 in the United States to describe state-level spatio-temporal heterogeneity in the waves of the epidemic. We obtained overdose death counts by state from 1999-2021. categorized as involving prescription opioids. heroin. https://www.lecoureures.shop/product-category/course-a-pied-femme-vetements-chandail-long-sleeves-brosse/